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Morphing of Alpha Synuclein

alpha_synuclein_morphOn 6th September, Science Daily reported that scientists at Purdue University have taken detailed images and measurements of the morphing structure of alpha synuclein. Alpha synuclein ordinarily exists in a globular shape. However, the protein morphs into harmful structures known as amyloid fibrils, which are linked to protein molecules that form in the brains of patients with Parkinson’s. Until now, the transition from globular to fibrils had not been captured and measured.The findings were detailed in a research paper appearing in the June issue of the Biophysical Journal 104(12) pp. 2706 – 2713.

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