Using cinnamon, a common food spice and flavouring material, can reverse the biomechanical, cellular and anatomical changes that occur in the brains of mice with Parkinson’s disease (PD), neurological scientists have found.The results of the study by a group at Rush University Medical Centre, led by Dr Kalipada Pahan, were published in the June 20 issue of the Journal of Neuroimmune Pharmacology.
The study found that after oral feeding, ground cinnamon is metabolized into sodium benzoate, which then enters into the brain, stops the loss of Parkin and DJ-1, protects neurons, normalizes neurotransmitter levels, and improves motor functions in mice with PD.
Saurabh Khasnavis, Kalipada Pahan. Cinnamon Treatment Upregulates Neuroprotective Proteins Parkin and DJ-1 and Protects Dopaminergic Neurons in a Mouse Model of Parkinson’s Disease. Journal of Neuroimmune Pharmacology, 2014; DOI: 10.1007/s11481-014-9552-2