Science Today reports that researchers at the University of Pittsburgh School of Medicine have uncovered a major reason why the Parkinson’s-related protein alpha-synuclein, a major constituent of the Lewy bodies that are the pathological hallmark of Parkinson’s disease (PD), is toxic to neurons in the brain. The finding has the potential to lead to new…
Mechanisms
New Animal Model Provides Important Clues On Mechanisms of Parkinson’s Disease
In a post dated 24 May, Science Daily reports that scientists at the German Centre for Neurodegenerative Diseases (DZNE) in Bonn have developed a novel experimental model that reproduces for the first time the pattern of alpha-synuclein brain spreading and provides important clues on the mechanisms underlying this pathological process. They triggered the production of…