Can cannabidiol (CBD) reduce symptoms of hallucinations and delusions in people with Parkinson’s?
Parkinson’s UK is funding research teams across the UK to investigate whether CBD could be an effective treatment for symptoms of Parkinson’s psychosis, such as hallucinations and delusions. A research centre is now open in Dundee.
Who do the researchers need?
120 people with Parkinson’s who,
o are over 40 years old
o have experienced any symptoms of psychosis for at least one month. This could include seeing, hearing, or feeling things that aren’t there and mistaking objects for other things (hallucinations). For example, a pile of clothes might look like a dog. Symptoms could also include unusual thoughts, beliefs, or worries that aren’t based on reality (delusions)
o have been stable on any Parkinson’s medications or antipsychotic treatment for at least one month
o are not taking clozapine
o and have someone who can attend study visits with them
What is involved?
If you are eligible to take part, you will either receive the study treatment (CBD) or a placebo (such as a sugar pill) for 12 weeks
You will be asked to attend up to 6 visits. Some of these can take place over the telephone or online, and others will need to take place at your local research centre or at your home
o Each visit will last between 1 and 3 hours
o during the visits you may be asked to give blood samples, complete surveys, or physical examinations
For more information, please read the participant information sheets:
o for people with Parkinson’s
o for accompanying loved one or carer
Interested in taking part?
The deadline for taking part in this research is 1 March 2025.
If you have any questions please contact the research team by email at canpdp.trialoffice@kcl.ac.uk or by phone on 07936545178.
(Notre: These opportunities are not managed by Parkinson’s UK).